1 March 2016 – 28 February 2018
Mauro DiNuzzo, Anne Walls, Lasse K. Bak, Gulin Oz, Elisabeth R. Seaquist, Helle S. Waagepetersen, Maiken Nedergaard, Arne Schousboe
A fundamental understanding of glycogen structure, concentration, polydispersity and turnover is critical to qualify the role of glycogen in the brain. …
Nadia Nielsen Aalling, Mauro DiNuzzo, Maiken Nedergaard
The goal of the present paper is to review current literature supporting the occurrence of fundamental changes in brain energy metabolism during the transition from wakefulness to sleep. …
Daniele Mascali, Mauro DiNuzzo, Laura Serra, Silvia Mangia, Bruno Maraviglia, Marco Bozzali, Federico Giove
Subtle semantic deficits can be observed in Alzheimer’s disease (AD) patients even in the early stages of the illness. …
Mauro DiNuzzo, Maiken Nedergaard
Brain activity during wakefulness is associated with high metabolic rates that are believed to support information processing and memory encoding. In spite of loss of consciousness, sleep still carries a substantial energy cost. …
Poster presentation at the International Society for Neurochemistry/European Society for Neurochemistry (ISN-ESN) 2017 Meeting, Paris, France, 20-24 August 2017
Mauro DiNuzzo, Simon Sanggaard, Serhii Kostrikov, Anna L. Xavier, Sofie Christensen, Blanca Aldana, Lasse K. Bak, Ursula Sonnewald, Arne Schousboe, Helle S. Waagepetersen, Maiken Nedergaard
PURPOSE: To investigate brain metabolism using intracisternal delivery of [U-13C]glucose, thus bypassing blood-brain barrier and avoiding effects of peripheral metabolism. …
Mauro DiNuzzo
Besides energy, what else does the brain need to function? Probably the way energy is allocated under the control of multiple trade-offs that ultimately shape optimal energy utilization and behavior. …
Mauro DiNuzzo, Daniele Mascali, Marta Moraschi, Giorgia Bussu, Bruno Maraviglia, Silvia Mangia, Federico Giove
Time-domain analysis of blood-oxygenation level-dependent (BOLD) signals allows the identification of clusters of voxels responding to photic stimulation in primary visual cortex (V1). …
Gulin Oz, Mauro DiNuzzo, Anjali Kumar, Amir Moheet, Ameer Khowaja, Kristine Kubisiak, Lynn E. Eberly, Elizabeth R. Seaquist
Supercompensated brain glycogen levels may contribute to the development of hypoglycemia-associated autonomic failure (HAAF) following recurrent hypoglycemia (RH) by providing energy for the brain during subsequent periods of hypoglycemia. …
Mauro DiNuzzo, Federico Giove, Bruno Maraviglia, Silvia Mangia
Brain activity involves essential functional and metabolic interactions between neurons and astrocytes. The importance of astrocytic functions to neuronal signaling is supported by many experiments reporting high rates of energy consumption and oxidative metabolism in these glial cells. …
